Efforts to combat misinformation surrounding mpox are intensifying as the vaccine rollout begins in the Democratic Republic of the Congo (DRC). A recent poll indicates that about half of the Congolese population is unaware of the deadly disease, which has allowed conspiracy theories and rumors to proliferate. Healthcare professionals in the DRC are not only battling the virus but also the misinformation that complicates their efforts. The initial shipments of the mpox vaccine, part of a larger commitment to provide millions of doses, have started to arrive. As the vaccination campaign is set to launch next month, the focus is shifting towards encouraging those in need to get vaccinated and educating communities on how to protect themselves from the virus.